Tia Utami at our laboratory received Bronze Award, 2022 Tissue Engineering and

Regenerative Medicine International Society, Asian-Pacific Capter (TERMIS-AP)

Student Paper Contest!

"Efficient Generation of Functional Liver Organoid from Human iPS Cells-Derived

CPM+ Liver Progenitor Cells using an Oxygen-Permeable Microwell Structure"

Tia Utami, Mathieu Danoy, Fumiya Tokito, Rubina Khadim, Hiroshi Arakawa,

Taketomo Kido, Atsushi Miyajima, Masaki Nishikawa, Yasuyuki Sakai

https://jsaae35.secand.net/img/hyoushou.pdf

Dhimas Agung Kuriniawan at our laboratory received "Hiroshi Itagaki Student

Encouragement Award"!

"Liver-small intestine drug metabolism-related crosstalk in vitro using on-chip

perfused anddirect oxygenated microphysiological system（MPS）"

Dhimas Kurniawan, Kousuke Inamura, Mathieu Danoy, Sylvia Leo,

Mutsumi Inamatsu, Sohei Funaoka, Daichi Aihara, Takeshi Sakura, Takumi Kawanishi,

Hiroshi Arakawa, Yukio Kato, Masaki Nishikawa, Nobuaki Shiraki, Shoen Kume,

Hiroshi Kimura, Yasuyuki Sakai

Article : https://www.t.u-tokyo.ac.jp/en/topics/tp2022-11-28-001

https://creektive.com/jsao2022/contents/award_02.html

Karn Changsorn at our laboratory received the 「Excellence Award,

Exploratory Research Poster Session, 60th Annual Meeting of the Japanese Society

for Artificial Organs (JSAO)！

"Free-form bioprinting of vascularized pancreatic tissue with high-density culture"

Karn Changsorn, Yuan Pang, Mathieu Danoy, Masaki Nishikawa, Wei Sun,

Yasuyuki Sakai

Article : https://www.t.u-tokyo.ac.jp/en/topics/tp2022-11-16-001

https://www.nikkakyo.org/news/page/9748

Masaki Nishikawa, a lecturer at our laboratory, received the 「7th Japan Chemical
　Industry Association Long-range Research Initiative」Award！

"Accurate Evaluation of Hepatocyte Metabolisms on a Nobel Oxygen-
　Permeable Material with Low Sorption Characteristics."

Article : http://www.t.u-tokyo.ac.jp/en/topics/tp2022-10-17-001

http://acaae2022.org/

・"Toward ideal prediction of human responses based on physiological in vitro

　systems"　

　Y. Sakai (invited)

・"Development of an in vitro liver culture system for continuous bile recovery"

　Fumiya Tokito, Yuya Nakazono, Mathieu Danoy, Hyunjin Choi,

　Hiroshi Arakawa, Ikumi Tamai, Masaki Nishikawa, Yasuyuki Sakai

　(Poster Presentation)

https://estiv.org/congress2022/

・"Latest activities of JSAAE toward establishment of Asian Federation"

　Yasuyuki Sakai, Hajime Kojima, Yasunari Kanda, Masato Hatao

・"Japanese MPS project I/II and a developed new MPS device with

　micro-stirrer-based on-chip perfusion and direct oxygenation"

　Yasuyuki Sakai, Dhimas A. Kurniawan, Mathieu Danoy, Hiroshi Kimura,

　Masaki Nishikawa (invited)

https://ap2022.termis.org/overview/

・"Integrating microwell structure and direct oxygenation to enhance functional

　liver organoid from hiPSCs-derived CPM+ liver progenitor cells"

　Tia Utami, Mathieu Danoy, Fumiya Tokito, Taketomo Kido, Masaki Nishikawa,

　Atsushi Miyajima, Yasuyuki Sakai (Oral Presentation)

・"Effect of direct oxygenation and coculture on primary hepatocytes & intestine

　epithelial cells cultured in stirrer-based microphysiological system (MPS) device"

　Dhimas Kurniawan, Kousuke Inamura, Mathieu Danoy, Sylvia Leo,

　Mutsumi Inamatsu, Sohei Funaoka, Daichi Aihara, Takeshi Sakura,

　Takumi Kawanishi, Hiroshi Arakawa, Yukio Kato, Masaki Nishikawa,

　Nobuaki Shiraki, Shoen Kume, Hiroshi Kimura,

　Yasuyuki Sakai (Poster Presentation)

・"Optimization of in vitro Culture Condition to Maintain Hepatic Stellate Cell

　in Quiescence"

　Ya Gong, Mathieu Danoy, Taketomo Kido, Masaki Nishikawa, Atsushi Miyajima,

　Yasuyuki Sakai (Poster Presentation)

https://eusaat.eu/eusaat-congress/23rd-edition/congress-2022/

・"Latest activities of JSAAE and Asian organization"

　Yasuyuki Sakai, Hajime Kojima, Yasunari Kanda and Masato Hatao (invited)

・"Enhanced metabolic functions of hepatocytes with aerobic respiration enabled

　by a new oxygen-permeable plate"

　Yasuyuki Sakai, Hiroyasu Ito, Fumiya Tokito, Mathieu Danoy, Takumi Kawanishi,

　Hiroshi Arakawa, Yukio Kato, Tomoaki Matsugi, Katsuhiro Esashika,

　Hiroshi Miyasako, Toru Sumita, Masaki Nishikawa

https://www.wcb2022.com/

・"A transcriptomic study on the influence of the stimulation by a microfluidic

　environment for the induction of zonation-like patterns in carboxypeptidase

　M-positive human pluripotent stem cells-derived liver progenitor cells"

　Mathieu Danoy, Stéphane Poulain, Benedikt Scheidecker, Soo Hyeon Kim,

　Taketomo Kido, Atsushi Miyajima, Yasuyuki Sakai, Eric Leclerc (invited)

https://mpsworldsummit.com/mps-world-summit-2022-3/

・“Overview of global MPS activities”

　Yasuyuki Sakai (invited, Roundtable Discussion )

・"Functional enhancements and crosstalk of liver-small intestine in a

　micro-stirrer-based on-chip perfusion MPS with direct oxygenation"

　Dhimas Agung Kurniawan, Kousuke Inamura, Danoy Mathieu, Sohei Funaoka,

　Daichi Aihara, Takeshi Sakura, Takumi Kawanishi, Hiroshi Arakawa, Yukio Kato,

　Masaki Nishikawa, Hiroshi Kimura and Yasuyuki Sakai (poster persentation No. 61)

・"Optimization of the in vitro culture environment to maintain quiescent

　hepatic stellate cell for development of liver microphysiological system"

　Ya Gong, Matheiu Danoy, Takemoto Kido, Misao Himeno, Masaki Nishikawa,

　Atsushi Miyajima and Yasuyuki Sakai (poster persentation No. 85)

・"Efficient generation of functional liver organoid from human iPS cells-derived

　CPM+ liver progenitor cells using an oxygenpermeable microwell structure"

　Tia Utami, Fumiya Tokito, Mathieu Danoy, Taketomo Kido, Atsushi Miyajima,

　Masaki Nishikawa and Yasuyuki Sakai (poster persentation No. 91)

https://www.eugloh.eu/events/tissue-and-organ-bioengineering-2022

・"Liver on chip"

　Y. Sakai(招待公演)